Genomic Epidemiology and Phylodynamic Analysis of Enterovirus A71 Reveal Its Transmission Dynamics in Asia-Reference-Cited by-同舟云学术

Genomic Epidemiology and Phylodynamic Analysis of Enterovirus A71 Reveal Its Transmission Dynamics in Asia

Published:2022-10-26 Issue:5 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Xiao Jinbo¹,Huang Keqiang¹,Lu Huanhuan¹,Song Yang¹,Han Zhenzhi¹,Zhang Man²,Li Jichen¹,Zhou Xiaofang³,Chen Jianhua⁴,Yu Qiuli⁵,Yang Ming⁶,Yan Dongmei¹,Ji Tianjiao¹,Yang Qian¹,Zhu Shuangli¹,Xu Wenbo¹⁷,Zhang Yong¹⁷

Affiliation:

1. WHO WPRO Regional Polio Reference Laboratory and National Health Commission Key Laboratory of biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of China

2. Shandong Center for Disease Control and Prevention, Jinan, Shandong, People’s Republic of China

3. Yunnan Center for Disease Control and Prevention, Kunming, Yunnan, People’s Republic of China

4. Gansu Center for Disease Control and Prevention, Lanzhou, Gansu, People’s Republic of China

5. Hebei Center for Disease Control and Prevention, Shijiazhuang, Hebei, People’s Republic of China

6. Heilongjiang Center for Disease Control and Prevention, Harbin, Heilongjiang, People’s Republic of China

7. Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, People’s Republic of China

Abstract

EV-A71 is one of the most important pathogens causing HFMD outbreaks; however, large-scale studies of EV-A71 genomic epidemiology are currently lacking. In this study, 200 new EV-A71 whole-genome sequences were determined.

Funder

MOST | National Key Research and Development Program of China

Natural Science Foundation of Beijing Municipality

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01958-22

Reference69 articles.

1. A second open reading frame in human enterovirus determines viral replication in intestinal epithelial cells

2. An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells