Prevalence and Homology of the Pneumococcal Serine-Rich Repeat Protein at the Global Scale-Reference-Cited by-同舟云学术

Prevalence and Homology of the Pneumococcal Serine-Rich Repeat Protein at the Global Scale

Published:2023-06-15 Issue:3 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Aceil Javid¹,Venkat Aarya¹,Pan Eric¹,Kannan Natarajan¹,Avci Fikri Y.¹²^ORCID

Affiliation:

1. Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA

2. Department of Biochemistry, Emory Vaccine Center, Emory University School of Medicine, Atlanta, Georgia, USA

Abstract

An updated outlook on PsrP prevalence and serotype distribution sheds new light on the comprehensiveness of a PsrP-based protein vaccine. The protein is present in all vaccine serotypes and highly present in the next wave of potentially disease-causing serotypes not included in the current multivalent conjugate vaccines.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Institute of General Medical Sciences

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.03252-22

Reference47 articles.

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