Diagnostic and Prognostic Value of Cerebrospinal Fluid Lactate and Glucose in HIV-Associated Tuberculosis Meningitis-Reference-Cited by-同舟云学术

Diagnostic and Prognostic Value of Cerebrospinal Fluid Lactate and Glucose in HIV-Associated Tuberculosis Meningitis

Published:2022-08-31 Issue:4 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Nuwagira Edwin¹²^ORCID,Huppler Hullsiek Kathy³,Jjunju Samuel²,Rutakingirwa Morris²,Kasibante John²,Tadeo Kiiza Kandole²,Kagimu Enock²,Tugume Lillian²⁴,Ssebambulidde Kenneth²,Musubire Abdu K.²⁴,Bangdiwala Ananta³,Muzoora Conrad¹²,Meya David B.²⁵⁴,Boulware David R.⁵^ORCID,Bahr Nathan C.⁶^ORCID,Creswell Fiona V.²⁷⁸

Affiliation:

1. Department of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda

2. Infectious Diseases Institute, Makerere University, Kampala, Uganda

3. Department of Biostatistics, University of Minnesota, Minneapolis, Minnesota, USA

4. School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda

5. Division of Infectious Diseases, Department of Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA

6. Division of Infectious Diseases, Department of Medicine, University of Kansas, Kansas City, Kansas, USA

7. MRC-UVRI-London School of Hygiene and Tropical Medicine Uganda Research Unit, Entebbe, Uganda

8. Clinical Research Department, London School of Hygiene and Tropical Medicine, London, United Kingdom

Abstract

Tuberculosis meningitis (TBM) is the most severe form of tuberculosis, and its fatality is largely due to delays in diagnosis. The role of CSF lactate has not been evaluated in patients with HIV presenting with signs and symptoms of meningitis.

Funder

HHS | NIH | National Institute of Neurological Disorders and Stroke

HHS | NIH | Fogarty International Center

HHS | NIH | National Institute of Allergy and Infectious Diseases

UKRI | Medical Research Council

Wellcome Trust

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01618-22