Rapid Detection of Antimicrobial Resistance in Mycoplasma genitalium by High-Resolution Melting Analysis with Unlabeled Probes

Author:

Li Yamei12,Xiu Leshan34,Wang Liqin12,Zhang Lulu12,Wang Feng5,Peng Junping12ORCID

Affiliation:

1. NHC Key Laboratory of Systems Biology of Pathogens, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

2. Key Laboratory of Respiratory Disease Pathogenomics, Chinese Academy of Medical Sciences, Beijing, China

3. School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, China

4. One Health Center, Shanghai Jiao Tong University-The University of Edinburgh, Shanghai, China

5. Shenzhen Center for Chronic Disease Control, Shenzhen, China

Abstract

Mycoplasma genitalium was recently added to the antimicrobial-resistant (AMR) threats “watch list” of the U.S. Centers for Disease Control and Prevention because this pathogen has become extremely difficult to treat as a result of increased resistance. M. genitalium is also difficult to culture, and therefore, molecule detection is the only method available for AMR testing.

Funder

CAMS Innovation Fund for Medical Sciences

Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences

MOE | Fundamental Research Funds for the Central Universities

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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