Modulating DNA Repair Pathways to Diversify Genomic Alterations in Saccharomyces cerevisiae-Reference-Cited by-同舟云学术

Modulating DNA Repair Pathways to Diversify Genomic Alterations in Saccharomyces cerevisiae

Published:2022-04-27 Issue:2 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Wang Zhen¹²,Lin Yuping¹³^ORCID,Dai Zongjie¹³,Wang Qinhong¹³^ORCID

Affiliation:

1. CAS Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China

2. College of Science & Technology, Hebei Agricultural University, Cangzhou, Hebei, China

3. National Center of Technology Innovation for Synthetic Biology, Tianjin, China

Abstract

Most of the published papers about nuclease-assisted genome editing focused on precision engineering in human cells. However, the topic of inducing mutagenesis via error-prone repair has often been ignored in yeast.

Funder

Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project

Research Equipment Program of Chinese Academy of Sciences

Natural Science Foundation of Hebei Province

Specialized Research Fund for the Doctoral Program of Hebei Agicultural University

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02326-21

Reference76 articles.

1. Yeast chromosomal engineering to improve industrially-relevant phenotypes

2. The Delitto Perfetto Approach to In Vivo Site‐Directed Mutagenesis and Chromosome Rearrangements with Synthetic Oligonucleotides in Yeast

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4. Precise Editing at DNA Replication Forks Enables Multiplex Genome Engineering in Eukaryotes

5. Tn-seq: high-throughput parallel sequencing for fitness and genetic interaction studies in microorganisms

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