Primary Infection May Be an Underlying Factor Contributing to Lethal Hemorrhagic Disease Caused by Elephant Endotheliotropic Herpesvirus 3 in African Elephants ( Loxodonta africana )

Author:

Pursell Taylor1,Spencer Clinton Jennifer L.1,Tan Jie1,Peng Rongsheng1,Qin Xiang2,Doddapaneni Harshavardhan2,Menon Vipin2,Momin Zeineen2,Kottapalli Kavya2,Howard Lauren3,Latimer Erin4,Heaggans Sarah5,Hayward Gary S.5,Ling Paul D.1

Affiliation:

1. Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA

2. Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA

3. San Diego Zoo Safari Park, San Diego Zoo Wildlife Alliance, Escondido, California, USA

4. Wildlife Health Sciences, Smithsonian’s National Zoo, Washington, DC, USA

5. Viral Oncology Program, Johns Hopkins School of Medicine, Baltimore, Maryland, USA

Abstract

Prior to 2019, only five cases of clinical disease from EEHV infection among African elephants had been documented. Since 2019, there have been at least seven EEHV-HD cases in North American zoos, resulting in three fatalities, all associated with EEHV3.

Funder

International Elephant Foundation

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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