A Recombinant Duck Plague Virus Containing the ICP27 Deletion Marker Provides Robust Protection in Ducks-Reference-Cited by-全球学者库

A Recombinant Duck Plague Virus Containing the ICP27 Deletion Marker Provides Robust Protection in Ducks

Published:2023-08-17 Issue:4 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Wu Ying¹²³⁴⁵,Liu Lu¹²³⁴⁵,Zhang Mengya¹²³⁴⁵,Zhan Haichuan¹²³⁴⁵,Wang Chenjia¹²³⁴⁵,Wang Mingshu¹²³⁴⁵,Chen Shun¹²³⁴⁵,Jia Renyong¹²³⁴⁵,Yang Qiao¹²³⁴⁵,Zhu Dekang¹²³⁴^ORCID,Liu Mafeng¹²³⁴⁵^ORCID,Zhao Xinxin¹²³⁴⁵,Zhang Shaqiu¹²³⁴⁵,Huang Juan¹²³⁴⁵,Ou Xumin¹²³⁴⁵,Mao Sai¹²³⁴⁵,Gao Qun¹²³⁴⁵,Sun Di¹²³⁴⁵,Tian Bin¹²³⁴⁵,Cheng Anchun¹²³⁴⁵^ORCID

Affiliation:

1. Engineering Research Center of Southwest Animal Disease Prevention and Control Technology, Ministry of Education of the People’s Republic of China, Chengdu, People’s Republic of China

2. International Joint Research Center for Animal Disease Prevention and Control of Sichuan Province, Chengdu, People’s Republic of China

3. Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Wenjiang, People’s Republic of China

4. Avian Disease Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Wenjiang, People’s Republic of China

5. Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Wenjiang, People’s Republic of China

Abstract

The development of distinguishable marker vaccines from natural infection is a key step toward eradicating duck plague. Here, we generated a recombinant DPV that carries an ICP27 deletion marker that could be easily distinguished from wild-type strain by molecular biological methods.

Funder

Program Sichuan Veterinary Medicine and drug Innovation Group of the China Agricultural Research System

MOA | Earmarked Fund for China Agriculture Research System

Natural Science Foundation of Sichuan Province

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00983-23

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