Senecavirus a 3D Interacts with NLRP3 to Induce IL-1β Production by Activating NF-κB and Ion Channel Signals-Reference-Cited by-同舟云学术

Senecavirus a 3D Interacts with NLRP3 to Induce IL-1β Production by Activating NF-κB and Ion Channel Signals

Published:2022-04-27 Issue:2 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Choudhury Sk Mohiuddin¹^ORCID,Ma XuSheng¹,Zeng ZongBo¹,Luo Zhikuan¹,Li Yuanyuan²,Nian XiaoFeng¹,Ma YongHua²,Shi Zhengwang¹,Song Rui¹,Zhu ZiXiang¹^ORCID,Cao Weijun¹,Pei Jingjing¹,Zheng HaiXue¹^ORCID

Affiliation:

1. State Key Laboratory of Veterinary Etiological Biology, National Foot and Mouth Disease Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu, China

2. Gansu Agricultural University, Lanzhou, Gansu, China

Abstract

Inflammation refers to the response of the immune system to viral, bacterial, and fungal infections or other foreign particles in the body, which can involve the production of a wide array of soluble inflammatory mediators. The NLRP3 inflammasome is one of the best-characterized inflammasome leading to IL-1β production and maturation.

Funder

National Natural Science Foundation of China

Key technologies R&D program of Gansu Province

Collaborative innovation project of CAAS

Development of Seneca virus vaccine project

Research funding from collaborative innovation

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02097-21