Potential Role of the Host-Derived Cell-Wall Binding Domain of Endolysin CD16/50L as a Molecular Anchor in Preservation of Uninfected Clostridioides difficile for New Rounds of Phage Infection-Reference-Cited by-同舟云学术

Potential Role of the Host-Derived Cell-Wall Binding Domain of Endolysin CD16/50L as a Molecular Anchor in Preservation of Uninfected Clostridioides difficile for New Rounds of Phage Infection

Published:2022-04-27 Issue:2 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Phothichaisri Wichuda¹,Chankhamhaengdecha Surang²,Janvilisri Tavan¹,Nuadthaisong Jirayu¹,Phetruen Tanaporn¹,Fagan Robert P.³,Chanarat Sittinan¹⁴^ORCID

Affiliation:

1. Department of Biochemistry, Faculty of Science, Mahidol University, Bangkok, Thailand

2. Department of Biology, Faculty of Science, Mahidol University, Bangkok, Thailand

3. School of Biosciences, Florey Institute, University of Sheffield, Sheffield, United Kingdom

4. Laboratory of Molecular Cell Biology, Center for Excellence in Protein and Enzyme Technology, Faculty of Science, Mahidol University, Bangkok, Thailand

Abstract

Endolysin is a peptidoglycan hydrolase encoded in a phage genome. The enzyme is attractive due to its potential use as antibacterial treatment.

Funder

Science achievement scholarship of Thailand

National research council of Thailand and Mahidol University

Center of Excellence on Medical Biotechnology

Research cluster: Multi-generation researchers grant from Mahidol university

Mahidol University

Research grant for new scholar from the ministry of higher education, science, research and innovation

QIAGEN life science research grant

UKRI | Medical Research Council

UKRI | Biotechnology and Biological Sciences Research Council