Staphylococcus aureus and Pseudomonas aeruginosa Isolates from the Same Cystic Fibrosis Respiratory Sample Coexist in Coculture-Reference-Cited by-同舟云学术

Staphylococcus aureus and Pseudomonas aeruginosa Isolates from the Same Cystic Fibrosis Respiratory Sample Coexist in Coculture

Published:2022-08-31 Issue:4 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Bernardy Eryn E.¹²,Raghuram Vishnu²³^ORCID,Goldberg Joanna B.²^ORCID

Affiliation:

1. Department of Biology, Elon University, Elon, North Carolina, USA

2. Division of Pulmonary, Asthma, Cystic Fibrosis, and Sleep, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA

3. Microbiology and Molecular Genetics Program, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, Georgia, USA

Abstract

Previous studies have shown that in laboratory settings, Pseudomonas aeruginosa generally kills Staphylococcus aureus . However, these bacteria are often found coinfecting the lungs of cystic fibrosis (CF) patients, which has been associated with worse patient outcomes.

Funder

HHS | National Institutes of Health

Cystic Fibrosis Foundation

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00976-22

Reference31 articles.

1. Cystic Fibrosis Foundation. 2021. Cystic Fibrosis Foundation patient registry 2020 annual data report. Cystic Fibrosis Foundation, Bethesda, MD

2. Association between Staphylococcus aureus alone or combined with Pseudomonas aeruginosa and the clinical condition of patients with cystic fibrosis