Salmonella Subpopulations Identified from Human Specimens Express Heterogenous Phenotypes That Are Relevant to Clinical Diagnosis

Author:

Gebremichael Yismashoa1,Crandall John1,Mukhopadhyay Rituparna1,Xu Fengfeng1ORCID

Affiliation:

1. Microbial Diseases Laboratory, California Department of Public Health, Richmond, California, USA

Abstract

In animal model systems, heterogenous Salmonella phenotypes were found previously to regulate bacterial infections. We describe in this communication that different Salmonella phenotypes also exist in infected humans at a single disease time point and that their phenotypic and molecular traits are associated with different aspects of pathogenicity.

Funder

California State General Fund

CDC Public Health ELC Fund

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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