NFAT5 Restricts Bovine Herpesvirus 1 Productive Infection in MDBK Cell Cultures

Author:

Liu Chang1,Lin Jiayu1,Yang Hao1,Li Ningxi1,Tang Linke1,Neumann Donna2,Ding Xiuyan1,Zhu Liqian13ORCID

Affiliation:

1. College of Life Sciences, Hebei University, Baoding, China

2. Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA

3. Key Laboratory of Microbial Diversity Research and Application of Hebei Province, College of Life Science, Hebei University, Baoding, China

Abstract

Accumulating studies have revealed that NFAT5 regulates disease development due to infection of numerous viruses, underlying the importance of the host factor in virus pathogenesis. Here, we report that NFAT5 has capacity to restrict BoHV-1 productive infection in vitro .

Funder

MOST | National Natural Science Foundation of China

National Natural Science Foundation of Hebei Province

National natural Science Foundation of Hebei Province

Foundation for the National Institutes of Health

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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