Multicenter Diagnostic Evaluation of a Novel Coronavirus Antigen Lateral Flow Test among Symptomatic Individuals in Brazil and the United Kingdom

Author:

Faffe Debora S.1,Byrne Rachel L.2ORCID,Body Richard34,Castiñeiras Terezinha Marta P.1,Castiñeiras Anna P.1,Finch Lorna S.2,Kontogianni Konstantina2,Bengey Daisy2,Galliez Rafael Mello1,Ferreira Orlando C.1,Mariani Diana1,da Silva Bianca Ortiz1,Ribeiro Sabrina Santana1,de Vos Margaretha5ORCID,Escadafal Camille5,Adams Emily R.2,Tanuri Amilcar1ORCID,Cubas Atienzar Ana I.2ORCID,Allen A. Joy,Braybrook Julian,Buckle Peter,Dark Paul,Davis Kerrie,Gordon Adam,Halstead Anna,Harden Charlotte,Inkson Colette,Jones Naoko,Jones William,Lasserson Dan,Lee Joseph,Lendrem Clare,Lewington Andrew,Logan Mary,Micocci Massimo,Nicholson Brian,Perera-Salazar Rafael,Prestwich Graham,Price D. Ashley,Reynard Charles,Riley Beverley,Simpson John,Tate Valerie,Turner Philip,Wilcox Mark,Zhifang Melody,Bengey Daisy,Buist Kate,Clerkin Karina,Edwards Thomas,Wardale Jahanara,Williams Christopher T.,Wooding Dominic, , , ,

Affiliation:

1. Universidade Federal do Rio de Janeiro (UFRJ), Núcleo de Enfrentamento e Estudos de Doenças Infecciosas e Emergentes e Reemergentes (NEEDIER), Rio de Janeiro, Brazil

2. Liverpool School of Tropical Medicine, Centre for Drugs and Diagnostics, Liverpool, United Kingdom

3. Oxford University, Oxford, United Kingdom

4. Manchester University NHS Foundation Trust, Manchester, United Kingdom

5. FIND, Geneva, Switzerland

Abstract

Since the beginning of the SARS-CoV-2 pandemic, we have witnessed growing numbers of antigen rapid diagnostic tests (Ag-RDTs) being brought to market. In the United Kingdom, this was somewhat controlled indirectly as the government offered free tests from a small number of companies.

Funder

Unitaid

Governments of the Netherlands

UK Department for International Development

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Reference16 articles.

1. WHO. 2020. Coronavirus disease 2019 (COVID-19) - situation report 51. WHO Geneva Switzerland.

2. Increased transmissibility and global spread of SARS-CoV-2 variants of concern as at June 2021

3. Department of Health and Social Care. 2020. COVID-19 testing data: methodology note. Department of Health and Social Care London United Kingdom.

4. Testing at scale during the COVID-19 pandemic

5. Rapid, point-of-care antigen and molecular-based tests for diagnosis of SARS-CoV-2 infection

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