Serum Antibody Activity against Poly- N -Acetyl Glucosamine (PNAG), but Not PNAG Vaccination Status, Is Associated with Protecting Newborn Foals against Intrabronchial Infection with Rhodococcus equi-Reference-Cited by-同舟云学术

Serum Antibody Activity against Poly- N -Acetyl Glucosamine (PNAG), but Not PNAG Vaccination Status, Is Associated with Protecting Newborn Foals against Intrabronchial Infection with Rhodococcus equi

Published:2021-09-03 Issue:1 Volume:9 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Cohen Noah D.¹^ORCID,Kahn Susanne K.¹,Cywes-Bentley Colette²,Ramirez-Cortez Sophia¹,Schuckert Amanda E.¹,Vinacur Mariana²,Bordin Angela I.¹^ORCID,Pier Gerald B.²

Affiliation:

1. Equine Infectious Disease Laboratory, Department of Large Animal Clinical Sciences, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, Texas, USA

2. Department of Medicine, Brigham & Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USA

Abstract

Pneumonia caused by R. equi is an important cause of disease and death in foals worldwide for which a licensed vaccine is lacking. Foals are exposed to R. equi in their environment from birth, and they appear to be infected soon after parturition at an age when innate and adaptive immune responses are diminished.

Funder

Morris Animal Foundation

Link Equine Research Endowent

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/Spectrum.00638-21

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3. Clinical manifestations, diagnosis, treatment, and prevention of Rhodococcus equi infections in foals

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5. Epidemiology of Rhodococcus equi infections: A review

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