Combined Treatment of 6-Gingerol Analog and Tobramycin for Inhibiting Pseudomonas aeruginosa Infections

Author:

Ham So-Young1,Kim Han-Shin2,Jo Min Jee3,Lee Jeong-Hoon1,Byun Youngjoo45,Ko Gang-Jee3,Park Hee-Deung16ORCID

Affiliation:

1. School of Civil, Environmental and Architectural Engineering, Korea University, Seoul, Republic of Korea

2. Korean Peninsula Infrastructure Cooperation Team, Korea Institute of Civil Engineering and Building Technology (KICT), Goyang-si, Gyeonggi-do, Republic of Korea

3. Department of Internal Medicine, College of Medicine, Korea University, Seoul, Republic of Korea

4. College of Pharmacy, Korea University, Sejong, Republic of Korea

5. Biomedical Research Center, Korea University Guro Hospital, Seoul, Republic of Korea

6. KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, Republic of Korea

Abstract

Pseudomonas aeruginosa is a pathogen that causes various infectious diseases through quorum-sensing regulation. Although antibiotics are mainly used to treat P. aeruginosa infections, they cause the emergence of resistant bacteria in humans.

Funder

National Research Foundation of Korea

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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