Proteomic Analysis of a Hypervirulent Mutant of the Insect-Pathogenic Fungus Metarhizium anisopliae Reveals Changes in Pathogenicity and Terpenoid Pathways-Reference-Cited by-同舟云学术

Proteomic Analysis of a Hypervirulent Mutant of the Insect-Pathogenic Fungus Metarhizium anisopliae Reveals Changes in Pathogenicity and Terpenoid Pathways

Published:2022-12-21 Issue:6 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Huang Wenyou¹,Huang Peiquan¹,Yü Dan¹,Li Chengzhou¹,Huang Shuaishuai²,Qi Ping³,Huang Song³,Keyhani Nemat O.²^ORCID,Huang Zhen¹^ORCID

Affiliation:

1. South China Agricultural University, College of Plant Protection, Key Laboratory of Bio-Pesticide Creation and Application of Guangdong Province, Guangzhou, China

2. Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, Florida, USA

3. Guangzhou Institute for Food Inspection, Guangzhou, China

Abstract

The mechanisms that underlie and contribute to microbial (fungal) virulence are known to be varied; however, the identification of contributing pathways beyond known virulence factors remains difficult. Using TMT-based proteomic analyses, changes in the proteomes of an M. anisopliae hypervirulent mutant and its wild-type parent were determined.

Funder

National key R & D program of China

Science and Technology Planning Project of Guangzhou City

National Key Technology Support Program China

GDSTC | Science and Technology Planning Project of Guangdong Province

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00760-22