LPS O Antigen Plays a Key Role in Klebsiella pneumoniae Capsule Retention-Reference-Cited by-同舟云学术

LPS O Antigen Plays a Key Role in Klebsiella pneumoniae Capsule Retention

Published:2022-08-31 Issue:4 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Singh Shweta¹,Wilksch Jonathan J.¹²,Dunstan Rhys A.²^ORCID,Mularski Anna¹,Wang Nancy¹,Hocking Dianna¹,Jebeli Leila¹,Cao Hanwei¹,Clements Abigail³^ORCID,Jenney Adam W. J.¹,Lithgow Trevor²^ORCID,Strugnell Richard A.¹^ORCID

Affiliation:

1. Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia

2. Infection and Immunity Program, Biomedicine Discovery Institute and Department of Microbiology, Monash University, Clayton, Victoria, Australia

3. Department of Life Sciences, Imperial College London, London, United Kingdom

Abstract

Bacterial capsules, typically comprised of complex sugars, enable pathogens to avoid key host responses to infection, including phagocytosis. These capsules are synthesized within the bacteria, exported through the outer envelope, and then secured to the external surface of the organism by a force or forces that are incompletely described.

Funder

Department of Health | National Health and Medical Research Council

Department of Education and Training | Australian Research Council

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01517-21

Reference85 articles.

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