Development and Validation of a Protein Array for Detection of Antibodies against the Tick-Borne Pathogen Borrelia miyamotoi-Reference-Cited by-同舟云学术

Development and Validation of a Protein Array for Detection of Antibodies against the Tick-Borne Pathogen Borrelia miyamotoi

Published:2022-12-21 Issue:6 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Hoornstra Dieuwertje¹^ORCID,Stukolova Olga A.²^ORCID,Karan Ludmila S.²,Sarksyan Denis S.³^ORCID,Kolyasnikova Nadezhda M.²⁴^ORCID,Markelov Mikhail L.⁵,Cherkashina Anna S.²^ORCID,Dolgova Anna S.⁶^ORCID,Sudina Anna E.²,Sokolova Marina I.²,Platonov Alexander E.²^ORCID,Hovius Joppe W.¹⁷

Affiliation:

1. Center for Experimental and Molecular Medicine, Amsterdam University Medical Centers, Academic Medical Center, Amsterdam, The Netherlands

2. Central Research Institute of Epidemiology, Moscow, Russia

3. Izhevsk State Medical Academy, Izhevsk, Russia

4. Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products, Russian Academy of Sciences, Moscow, Russia

5. Izmerov Research Institute of Occupational Health, Moscow, Russia

6. St. Petersburg Pasteur Institute of Epidemiology and Microbiology, Saint Petersburg, Russia

7. Amsterdam Infection & Immunity Institute, Amsterdam University Medical Centers, Academic Medical Center, Amsterdam, The Netherlands

Abstract

This paper describes the protein array as a novel serological test for the diagnosis ofBorrelia miyamotoidisease (BMD), by reporting the methodology, the development of a diagnostic algorithm, and its extensive validation. With rising numbers of ticks and tick bites, tick-borne diseases, such as BMD, urgently deserve further societal and medical attention.B. miyamotoiis prevalent inIxodesticks across the northern hemisphere.

Funder

EC | European Regional Development Fund

Russian Science Foundation

ZonMw

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02036-22

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1. Epidemiology of relapsing fever borreliosis in Europe