Hydroxyl Radical Overproduction in the Envelope: an Achilles’ Heel in Peptidoglycan Synthesis-Reference-Cited by-同舟云学术

Hydroxyl Radical Overproduction in the Envelope: an Achilles’ Heel in Peptidoglycan Synthesis

Published:2022-02-23 Issue:1 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Giacomucci Sean¹^ORCID,Alvarez Laura²³^ORCID,Rodrigues Christopher D. A.⁴⁵^ORCID,Cava Felipe²³^ORCID,Paradis-Bleau Catherine¹

Affiliation:

1. Département de Microbiologie, Infectiologie et Immunologie, Faculté de Médecine, Université de Montréal, Montréal, Québec, Canada

2. Molecular Infection Medicine Sweden, Umea University, Umeå, Sweden

3. Umea Center for Microbial Research, Umea University, Umeå, Sweden

4. iThree Institute, University of Technology Sydney, Ultimo, New South Wales, Australia

5. School of Life Sciences, University of Warwick, Coventry, United Kingdom

Abstract

Oxidative stress is caused by the production and excessive accumulation of oxygen reactive species. In bacterial cells, oxidative stress mediated by hydroxyl radicals is typically associated with DNA damage in the cytoplasm.

Funder

Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada

Kempestiftelserna

Vetenskapsrådet

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01203-21

Reference75 articles.

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3. Normal growth and division of Escherichia coli with a reduced amount of murein

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5. An oldie but a goodie – cell wall biosynthesis as antibiotic target pathway

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