Spread of Carbapenem-Resistant Klebsiella pneumoniae Clinical Isolates Producing NDM-Type Metallo-β-Lactamase in Myanmar

Author:

Takei Satomi12,Lu Yu Jie3,Tohya Mari3,Watanabe Shin4,Misawa Shigeki1,Tabe Yoko2,Miida Takashi2,Mya San5,Tin Htay Htay5,Tada Tatsuya3ORCID,Kirikae Teruo3ORCID

Affiliation:

1. Department of Clinical Laboratory, Juntendo University Hospital, Tokyo, Japan

2. Department of Clinical Laboratory Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan

3. Department of Microbiology, Juntendo University Graduate School of Medicine, Tokyo, Japan

4. Department of Microbiome Research, Juntendo University Graduate School of Medicine, Tokyo, Japan

5. National Health Laboratory, Yangon, Myanmar

Abstract

The emergence of carbapenem-resistant K. pneumoniae has become a serious problem in medical settings worldwide. The present study demonstrated that carbapenem-resistant K. pneumoniae strains have been spreading in medical settings in Myanmar. In particular, plasmid genes encoding NDMs and 16S rRNA methylases have been spreading in K. pneumoniae high-risk clones.

Funder

Japan Agency for Medical Research and Development

Asahi Group Holdings

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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