Early Neonatal Meconium Does Not Have a Demonstrable Microbiota Determined through Use of Robust Negative Controls with cpn 60-Based Microbiome Profiling-Reference-Cited by-同舟云学术

Early Neonatal Meconium Does Not Have a Demonstrable Microbiota Determined through Use of Robust Negative Controls with cpn 60-Based Microbiome Profiling

Published:2021-10-31 Issue:2 Volume:9 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Dos Santos Scott J.¹^ORCID,Pakzad Zahra²³,Elwood Chelsea N.²⁴,Albert Arianne Y. K.²,Gantt Soren⁵,Manges Amee R.⁶,Dumonceaux Tim J.⁷^ORCID,Maan Evelyn J.²,Hill Janet E.¹^ORCID,Money Deborah M.²⁴^ORCID,

Affiliation:

1. Department of Veterinary Microbiology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

2. Women’s Health Research Institute, B.C. Women’s Hospital, Vancouver, British Columbia, Canada

3. Department of Microbiology and Immunology, Faculty of Science, University of British Columbia, Vancouver, British Columbia, Canada

4. Department of Obstetrics and Gynaecology, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada

5. Centre de Recherche du CHU Sainte-Justine, Quebec, Canada

6. School of Population and Public Health, Faculty of Medicine, University of British Columbia, British Columbia, Canada

7. Agriculture and Agri-Food Canada, Saskatoon, Saskatchewan, Canada

Abstract

Much like the recent placental microbiome controversy, studies of neonatal meconium reporting bacterial communities within the fetal and neonatal gut imply that microbial colonization begins prior to birth. However, recent work has shown that placental microbiomes almost exclusively represent contamination from lab reagents and the environment.

Funder

Gouvernement du Canada | Canadian Institutes of Health Research

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/Spectrum.00067-21

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