mRNA Vaccine Mitigates SARS-CoV-2 Infections and COVID-19

Author:

Kackos Christina M.12ORCID,Surman Sherri L.1,Jones Bart G.1,Sealy Robert E.1,Jeevan Trushar1,Davitt Christopher J. H.3,Pustylnikov Sergei3,Darling Tamarand L.4,Boon Adrianus C. M.456ORCID,Hurwitz Julia L.1,Samsa Marcelo M.3,Webby Richard J.1ORCID

Affiliation:

1. Department of Infectious Diseases, St. Jude Children’s Research Hospital, Memphis, Tennessee, USA

2. St. Jude Children’s Research Hospital Graduate School of Biomedical Sciences, Memphis, Tennessee, USA

3. GreenLight Biosciences, Woburn, Massachusetts, USA

4. Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA

5. Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, USA

6. Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA

Abstract

SARS-CoV-2 continues to disrupt everyday life and cause excess morbidity and mortality worldwide. Vaccination has been key to quelling the impact of this respiratory pathogen, and mRNA vaccines have led the charge on this front.

Funder

GreenLight Bioscience

American Lebanese Syrian Associated Charities

HHS | NIH | National Cancer Institute

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Reference35 articles.

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2. An interactive web-based dashboard to track COVID-19 in real time

3. Anonymous. 2021. Comirnaty and Pfizer-BioNTech COVID-19 vaccine on U. S. Food and Drug Administration. https://www.fda.gov/emergency-preparedness-and-response/coronavirus-disease-2019-covid-19/comirnaty-and-pfizer-biontech-covid-19-vaccine.

4. Anonymous. 2021. Moderna COVID-19 vaccine on U. S. Food and Drug Administration. https://www.fda.gov/emergency-preparedness-and-response/coronavirus-disease-2019-covid-19/moderna-covid-19-vaccine.

5. Anonymous. 2021. Janssen COVID-19 vaccine on U. S. Food and Drug Administration. https://www.fda.gov/emergency-preparedness-and-response/coronavirus-disease-2019-covid-19/janssen-covid-19-vaccine.

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