Rapid Detection of Clarithromycin and Amikacin Resistance in Mycobacterium abscessus Complex by High-Resolution Melting Curve Analysis

Author:

Li Haoran1,Mulati Gulibike2,Shang Yuanyuan1,Yao Cong1,Wang Yufeng3,Ren Weicong1,Xue Zhongtan3,Li Shanshan1,Pang Yu1ORCID

Affiliation:

1. Department of Bacteriology and Immunology, Beijing Chest Hospital, Capital Medical University/Beijing Tuberculosis and Thoracic Tumor Research Institute, Tongzhou District, Beijing, People’s Republic of China

2. Department of Laboratory Medicine, The Eighth Affiliated Hospital of Xinjiang Medical University Urumqi, Xinjiang, People's Republic of China

3. Department of Laboratory Quality Control, Innovation Alliance on Tuberculosis Diagnosis and Treatment (Beijing), Beijing, People’s Republic of China

Abstract

Mycobacterium abscessus complex (MABC) has attracted increasing attention due to the numerous cases of infection. This pathogen is notorious for its intrinsic drug resistance, which complicates clinical management of patients with MABC infections.

Funder

Beijing Hospital Authority Ascent Plan

Beijing Hospital Authority Clinical Medicine Development of Special Funding

Capital's Funds For Health Improvement and Research

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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