Comparative In Vitro Study of Biofilm Formation and Antimicrobial Susceptibility in Gram-Negative Bacilli Isolated from Prosthetic Joint Infections

Author:

Macias-Valcayo Alicia1,Aguilera-Correa John-Jairo12,Broncano Antonio1,Parron Raul23,Auñon Alvaro23,Garcia-Cañete Joaquin4,Blanco Antonio24,Esteban Jaime12ORCID

Affiliation:

1. Department of Clinical Microbiology, Instituto de Investigación Sanitaria (IIS)-Fundación Jiménez Díaz, Universidad Autónoma de Madrid (UAM), Madrid, Spain

2. Centre for Biomedical Research Network in Infectious Diseases (CIBERINFEC), CIBER de Enfermedades Infecciosas, Madrid, Spain

3. Department of Orthopaedic Surgery, Fundación Jiménez Díaz, Madrid, Spain

4. Department of Internal Medicine-Emergencies, Fundación Jiménez Díaz, Madrid, Spain

Abstract

This study is the first one to analyze a high number of isolates of Gram-negative bacilli that are the cause of prosthetic joint infection. The analysis includes biofilm development and antimicrobial susceptibility testing of both planktonic and sessile bacteria. The obtained results support the clinical knowledge about the treatment of these bacteria when biofilms are involved.

Funder

Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica

CIBERINFEC

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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