The Type IV Pilus of Plasmid TP114 Displays Adhesins Conferring Conjugation Specificity and Is Important for DNA Transfer in the Mouse Gut Microbiota

Author:

Allard Nancy1,Neil Kevin1,Grenier Frédéric1,Rodrigue Sébastien1ORCID

Affiliation:

1. Département de biologie, Faculté des sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada

Abstract

Conjugative plasmids are involved in horizontal gene transfer in the gut microbiota, which constitutes an important antibiotic resistance gene reservoir. However, the molecular mechanisms used by conjugative plasmids to select recipient bacteria and transfer at high rates in the mouse gut microbiota remain poorly characterized.

Funder

Gouvernement du Canada | Canadian Institutes of Health Research

FRQ | Fonds de Recherche du Québec - Santé

Université de Sherbrooke

FRQ | Fonds de recherche du Québec - Nature et technologies

Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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