Host Polyunsaturated Fatty Acids Potentiate Aminoglycoside Killing of Staphylococcus aureus-Reference-Cited by-同舟云学术

Host Polyunsaturated Fatty Acids Potentiate Aminoglycoside Killing of Staphylococcus aureus

Published:2022-04-27 Issue:2 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Beavers William N.¹²^ORCID,Munneke Matthew J.¹,Stackhouse Alex R.²,Freiberg Jeffrey A.¹³^ORCID,Skaar Eric P.¹⁴⁵^ORCID

Affiliation:

1. Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA

2. Department of Pathobiological Sciences, Louisiana State University and Agricultural and Mechanical College, School of Veterinary Medicine, Baton Rouge, Louisiana, USA

3. Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA

4. Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, Tennessee, USA

5. Vanderbilt Institute for Chemical Biology, Vanderbilt University, Nashville, Tennessee, USA

Abstract

Staphylococcus aureus infects every niche of the human host, and these infections are the leading cause of Gram-positive sepsis. Aminoglycoside antibiotics are inexpensive, stable, and effective against many bacterial infections.

Funder

American Heart Association

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Institute of Environmental Health Sciences

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02767-21

Reference27 articles.

1. Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management