Enhanced Pathogenesis Caused by Influenza D Virus and Mycoplasma bovis Coinfection in Calves: a Disease Severity Linked with Overexpression of IFN-γ as a Key Player of the Enhanced Innate Immune Response in Lungs-Reference-Cited by-同舟云学术

Enhanced Pathogenesis Caused by Influenza D Virus and Mycoplasma bovis Coinfection in Calves: a Disease Severity Linked with Overexpression of IFN-γ as a Key Player of the Enhanced Innate Immune Response in Lungs

Published:2021-12-22 Issue:3 Volume:9 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Lion Adrien¹,Secula Aurélie¹,Rançon Camille¹,Boulesteix Olivier²,Pinard Anne²,Deslis Alain²,Hägglund Sara³,Salem Elias¹,Cassard Hervé¹,Näslund Katarina³,Gaudino Maria¹,Moreno Ana⁴,Brocchi Emiliana⁴,Delverdier Maxence¹,Zohari Siamak⁵,Baranowski Eric¹,Valarcher Jean-François³,Ducatez Mariette F.¹,Meyer Gilles¹^ORCID

Affiliation:

1. IHAP, UMR1225, Université de Toulouse, INRAE, Ecole Vétérinaire de Toulouse, Toulouse, France

2. INRAE, UE 1277, Experimental Infectiology Platform (PFIE), INRA-Val de Loire Research Centre, Nouzilly, France

3. Swedish University of Agricultural Sciences, Host Pathogen Interaction Group, Department of Clinical Sciences, Uppsala, Sweden

4. Istituto Zooprofilattico Sperimentale Della Lombardia e dell’Emilia Romagna Bruno Ubertini, Brescia, Italy

5. Department of Virology, Immunobiology and Parasitology, National Veterinary Institute, Uppsala, Sweden

Abstract

Bovine respiratory disease (BRD) is among the most prevalent diseases in young cattle. BRD is due to complex interactions between viruses and/or bacteria, most of which have a moderate individual pathogenicity.

Funder

Agence Nationale de la Recherche

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01690-21

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