Qualitative and Quantitative Detection of Multiple Sexually Transmitted Infection Pathogens Reveals Distinct Associations with Cervicitis and Vaginitis

Author:

Kang Wen-Tyng123,Xu Haibo123,Liao Yiqun123,Guo Qiwei45,Huang Qiuying123,Xu Ye123,Li Qingge123ORCID

Affiliation:

1. Engineering Research Centre of Molecular Diagnostics, Ministry of Education, State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, Fujian, China

2. State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen, Fujian, China

3. Engineering Research Centre of Personalized Molecular Diagnostics of Xiamen, Xiamen, Fujian, China

4. Xiamen Maternal and Child Health Hospital, Xiamen, Fujian, China

5. United Diagnostic and Research Center for Clinical Genetics, School of Public Health of Xiamen University, Xiamen, Fujian, China

Abstract

Scarce information exists with regard to whether STI pathogens can be defined as valid microbiological predictive markers for the diagnosis of cervicitis and vaginitis. We therefore conducted this study to assess the presence and abundance of a wide range of STI pathogens among patients having these two diseases and healthy controls as well.

Funder

Xiamen Municipal Bureau of Science and Technology

Fujian Provincial Department of Science and Technology

Key Bio-safety Research and Development Technology Project

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Reference41 articles.

1. Centers for Disease Control and Prevention. 2019. Sexually transmitted disease surveillance 2018. U.S. Department of Health and Human Services, Atlanta, GA.

2. World Health Organization. 2018. Report on global sexually transmitted infection surveillance, 2018. World Health Organization, Geneva, Switzerland.

3. Incidence Trends of Five Common Sexually Transmitted Infections Excluding HIV From 1990 to 2019 at the Global, Regional, and National Levels: Results From the Global Burden of Disease Study 2019

4. Diagnosis and Treatment of Sexually Transmitted Infections

5. HIV pre-exposure prophylaxis and sexually transmitted infections: intersection and opportunity

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