Dynamics of Humoral Immunity to Myxoma and Rabbit Hemorrhagic Disease Viruses in Wild European Rabbits Assessed by Longitudinal Semiquantitative Serology

Author:

Coelho Joana12,Pacheco Henrique12,Rafael Marta234,Jiménez-Ruiz Saúl2345,Alves Paulo Célio2367,Santos Nuno237ORCID

Affiliation:

1. CIISA—Centro de Investigação Interdisciplinar em Sanidade Animal, Faculty of Veterinary Medicine, University of Lisbon, Lisbon, Portugal

2. CIBIO, Centro de Investigação em Biodiversidade e Recursos Genéticos, InBIO Laboratório Associado, Universidade do Porto, Vairão, Portugal

3. BIOPOLIS Program in Genomics, Biodiversity and Land Planning, CIBIO, Vairão, Portugal

4. SABIO-IREC, Research Group in Health and Biotechnology, Institute for Game and Wildlife Research, University of Castilla-La Mancha, Castilla-La Mancha, Spain

5. GISAZ-ENZOEM, Animal Health and Zoonoses Research Group, Competitive Research Unit on Zoonoses and Emerging Diseases, University of Cordoba, Cordoba, Spain

6. Departamento de Biologia, Faculdade de Ciências, Universidade do Porto, Porto, Portugal

7. Estação Biológica de Mértola (EBM), CIBIO, Mértola, Portugal

Abstract

This study addresses the long-term dynamics of humoral immunity to two major viral pathogens of the European rabbit, an endangered keystone species of major ecological relevance. Such studies are particularly challenging in free-ranging species, and a combination of longitudinal capture-mark-recapture and semiquantitative serology was used to address this question.

Funder

Universidad Castilla-la-Mancha

EC | European Regional Development Fund

MEC | Fundação para a Ciência e a Tecnologia

Ministerio de Ciencia e Innovación

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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