Antimicrobial Peptide Combination Can Hinder Resistance Evolution-Reference-Cited by-同舟云学术

Antimicrobial Peptide Combination Can Hinder Resistance Evolution

Published:2022-08-31 Issue:4 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Maron Bar¹²,Rolff Jens³,Friedman Jonathan²^ORCID,Hayouka Zvi¹^ORCID

Affiliation:

1. Institute of Biochemistry, Food Science and Nutrition, The Hebrew University of Jerusalem, Rehovot, Israel

2. Department of Plant Pathology and Microbiology, The Hebrew University of Jerusalem, Rehovot, Israel

3. Institute of Biology, Evolutionary Biology, Freie University, Berlin, Germany

Abstract

The main insights gleaned from this study are the following. (i) AMP combination treatment can delay the evolution of resistance in S. aureus . Treatment with some AMP pairs resulted in significantly lower resistance then treatment with either of the individual AMPs.

Funder

Ministry of Science and Technology

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00973-22

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