Specificity of Immunoglobulin Response to Nontuberculous Mycobacteria Infection in People with Cystic Fibrosis

Author:

Malcolm Kenneth C.12ORCID,Wheeler Emily A.1,Calhoun Kara2ORCID,Lenhart-Pendergrass Patricia M.3,Rysavy Noel1,Poch Katie R.1,Caceres Silvia M.1,Saavedra Milene T.12,Nick Jerry A.12ORCID

Affiliation:

1. Department of Medicine, National Jewish Health, Denver, Colorado, USA

2. Department of Medicine, University of Colorado, Aurora, Colorado, USA

3. Department of Pediatrics, University of Colorado, Aurora, Colorado, USA

Abstract

Lung infections with nontuberculous mycobacteria (NTM), and particularlyMycobacterium abscessus, a pathogen with high antibiotic resistance, are of great concern due to poor clinical outcomes and challenging detection in people with cystic fibrosis and other diseases. Standard detection methods are insensitive and increasingly difficult.

Funder

Cystic Fibrosis Foundation

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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