Retrospective Performance Analyses of over Two Million U.S. QuantiFERON Blood Sample Results

Author:

Bi Caixia1,Clark Richard B.1,Master Ronald1,Kapoor Hema1,Kroll Martin H.1,Salm Ann E.1,Meyer William A.1

Affiliation:

1. Quest Diagnostics, Secaucus, New Jersey, USA

Abstract

Both the QuantiFERON-TB Gold Plus (QFT-Plus) and the QuantiFERON-TB Gold In-Tube (QFT-GIT) tests are interferon gamma (IFN-γ) release assays (IGRAs) intended to detect in vitro cell-mediated immune responses to Mycobacterium tuberculosis antigens. In this study, we retrospectively analyzed performance data for both the QFT-GIT and QFT-Plus test systems from over 2 million samples.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Reference43 articles.

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3. Screening for Latent Tuberculosis Infection in Adults

4. Tuberculosis Screening, Testing, and Treatment of U.S. Health Care Personnel: Recommendations from the National Tuberculosis Controllers Association and CDC, 2019

5. Qiagen. 2019. QuantiFERON-TB Gold Plus (QFT-Plus) ELISA package insert. https://www.quantiferon.com/wp-content/uploads/2020/01/L1083163-R06-QF-TB-Gold-Plus-ELISA-IFU-CE.pdf. Retrieved 25 February 2021.

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