Genomic Epidemiology and Characterization of Carbapenem-Resistant Klebsiella pneumoniae in ICU Inpatients in Henan Province, China: a Multicenter Cross-Sectional Study-Reference-Cited by-同舟云学术

Genomic Epidemiology and Characterization of Carbapenem-Resistant Klebsiella pneumoniae in ICU Inpatients in Henan Province, China: a Multicenter Cross-Sectional Study

Published:2023-06-15 Issue:3 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Wang Shanmei¹,Wang Lei²,Jin Jing³,Li Gang¹,Shao Huanzhang⁴,Song Yang²,Sun Yuanzheng⁵,Zhang Yan⁶,Cheng Jianjian⁷^ORCID,Li Lifeng²

Affiliation:

1. Department of Clinical Microbiology, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan University People's Hospital, Zhengzhou, Henan, China

2. Department of Bioinformatics Research, Genskey Co., Ltd., Beijing, China

3. Department of Pathogen Biology and Immunology, Henan Medical College, Zhengzhou, Henan, China

4. Department of Critical Care Medicine, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan University People's Hospital, Zhengzhou, Henan, China

5. Clinical Laboratory, Yuzhou Jundu Hospital, Xuchang, Henan, China

6. Clinical Laboratory, Yima People’s Hospital, Sanmenxia, Henan, China

7. Department of Respiratory and Critical Care Medicine, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Henan University People's Hospital, Zhengzhou, Henan, China

Abstract

In this study, we address the ongoing epidemic of carbapenem-resistant Klebsiella pneumoniae , a critical threat to public health. The alarming genotypic and phenotypic convergence of multidrug resistance and virulence highlights the increasingly aggravated threat posed by K. pneumoniae .

Funder

河南省科学技术厅 | Henan Provincial Science and Technology Research Project

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.04197-22

Reference92 articles.

1. Molecular pathogenesis of Klebsiella pneumoniae

2. Klebsiella pneumoniae liver abscess: a new invasive syndrome

3. Resistance reported from China antimicrobial surveillance network (CHINET) in 2018

4. World health organization releases global priority list of antibiotic-resistant bacteria to guide research, discovery, and development of new antibiotics

5. Infections Caused by Carbapenem-Resistant Enterobacteriaceae: An Update on Therapeutic Options