Minilungs from Human Embryonic Stem Cells to Study the Interaction of Streptococcus pneumoniae with the Respiratory Tract

Author:

Sempere Julio12,Rossi Suélen Andreia134,Chamorro-Herrero Irene1,González-Camacho Fernando2,de Lucas María Pilar5,Rojas-Cabañeros José María5,Taborda Carlos Pelleschi3,Zaragoza Óscar4ORCID,Yuste José2ORCID,Zambrano Alberto1ORCID

Affiliation:

1. Biotechnology of Stem Cells and Organoids, Chronic Diseases Program, Instituto de Salud Carlos III, Madrid, Spain

2. Spanish Pneumococcal Reference Laboratory, Centro Nacional de Microbiología, and CIBER of Respiratory Diseases (CIBERES), Instituto de Salud Carlos III, Madrid, Spain

3. Department of Microbiology, Biomedical Sciences Institute, University of São Paulo (USP), São Paulo, Brazil

4. Mycology Reference Laboratory, Centro Nacional de Microbiología and CIBER of Infectious Diseases (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain

5. Cellular Biology Unit, Chronic Diseases Program and CIBER of Cancer (CIBERONC), Instituto de Salud Carlos III, Madrid, Spain

Abstract

Streptococcus pneumoniaeis responsible for high morbidity and mortalities rates worldwide, affecting mainly children and adults older than 65 years. Pneumococcus is also the most common etiologic agent of bacterial pneumonia and nonepidemic meningitis, and it is a frequent cause of bacterial sepsis.

Funder

MEC | Instituto de Salud Carlos III

Ministerio de Ciencia, Innovación y Universidades

Fundación Científica Asociación Española Contra el Cáncer

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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