Discovery of Novel Iminosugar Compounds Produced by <i>Lactobacillus paragasseri</i> MJM60645 and Their Anti-Biofilm Activity against Streptococcus mutans-Reference-Cited by-同舟云学术

Discovery of Novel Iminosugar Compounds Produced by Lactobacillus paragasseri MJM60645 and Their Anti-Biofilm Activity against Streptococcus mutans

Published:2022-08-31 Issue:4 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Gu Mingkun¹,Cheng Jinhua²^ORCID,Lee Yeong-Geun³,Cho Joo-Hyung²,Suh Joo-Won²^ORCID

Affiliation:

1. Interdisciplinary Program of Biomodulation, Myongji University, Yongin, Republic of Korea

2. Myongji Bioefficacy Research Center, Myongji University, Yongin, Republic of Korea

3. Department of Oriental Medicine Biotechnology, College of Life Sciences, Kyung Hee University, Yongin, Republic of Korea

Abstract

In this study, we isolated lactic acid bacteria that inhibit streptococcal biofilm from the oral cavity of infants and identified two novel compounds from the supernatant of their culture broth. The two compounds are structurally similar, and both consist of iminosugars, glycerol, and unsaturated fatty acid.

Funder

Rural Development Administration

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01122-22

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