Role of Extracellular DNA in Dalbavancin Activity against Methicillin-Resistant Staphylococcus aureus (MRSA) Biofilms in Patients with Skin and Soft Tissue Infections-Reference-Cited by-同舟云学术

Role of Extracellular DNA in Dalbavancin Activity against Methicillin-Resistant Staphylococcus aureus (MRSA) Biofilms in Patients with Skin and Soft Tissue Infections

Published:2022-04-27 Issue:2 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Sivori Francesca¹,Cavallo Ilaria¹,Kovacs Daniela²,Guembe Maria³^ORCID,Sperduti Isabella⁴,Truglio Mauro²,Pasqua Martina⁵,Prignano Grazia¹,Mastrofrancesco Arianna¹,Toma Luigi⁶,Pimpinelli Fulvia¹,Morrone Aldo⁷,Ensoli Fabrizio¹,Di Domenico Enea Gino¹⁵^ORCID

Affiliation:

1. Microbiology and Virology, IRCCS San Gallicano Dermatological Institute, Rome, Italy

2. Cutaneous Physiopathology, San Gallicano Dermatological Institute, IRCCS, Rome, Italy

3. Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain

4. Biostatistical Unit-Clinical Trials Center, IRCCS Regina Elena National Cancer Institute, Rome, Italy

5. Department of Biology and Biotechnology “C. Darwin”, Sapienza University, Rome, Italy

6. Department of Research, Advanced Diagnostics, and Technological Innovation, Translational Research Area, IRCCS Regina Elena National Cancer Institute, Rome, Italy

7. Scientific Direction, IRCCS San Gallicano Dermatological Institute, Rome, Italy

Abstract

Staphylococcus aureus is the most common cause of skin and soft tissue infections (SSTIs) worldwide. In addition, methicillin-resistant S. aureus (MRSA) is increasingly frequent in postoperative infections and responsible for a large number of hospital readmissions and deaths.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00351-22

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