Association between Timing of Colonization and Risk of Developing Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae Infection in Hospitalized Patients-Reference-Cited by-同舟云学术

Association between Timing of Colonization and Risk of Developing Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae Infection in Hospitalized Patients

Published:2022-04-27 Issue:2 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Cano Ángela¹²,Gutiérrez-Gutiérrez Belén²³⁴^ORCID,Machuca Isabel¹²,Torre-Giménez Julián¹,Gracia-Ahufinger Irene²³⁵,Natera Alejandra M.¹²³,Pérez-Nadales Elena¹²³,Castón Juan Jose¹²³,Rodríguez-Baño Jesús²³⁴^ORCID,Martínez-Martínez Luis²³⁵⁶,Torre-Cisneros Julián¹²³^ORCID

Affiliation:

1. Infectious Diseases Unit, Hospital Universitario Reina Sofía-Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC)–Universidad de Córdoba, Córdoba, Spain

2. Centro de Investigación Biomédica en Red en Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Seville, Spain

3. Infectious Diseases Unit, Hospital Universitario Virgen Macarena–Instituto de Biomedicina de Seville (IBiS)-CSIC, Seville, Spain

4. Department of Medicine, Universidad de Seville, Seville, Spain

5. Microbiology Unit, Hospital Universitario Reina Sofía-IMIBIC, Córdoba, Spain

6. Department of Microbiology, University of Cordoba (UCO), Cordoba, Spain

Abstract

In this study, it was confirmed that patients who became colonized during hospitalization had a higher risk of developing KPC-Kp infection than hospitalized patients who were already colonized at the start of follow-up. Besides, the risk of infection in the group of patients who became colonized during follow-up was greater in the first weeks immediately after colonization was confirmed.

Funder

Instituto de Salud Carlos III

Instituto de Salud Carlos III- Spanish Network for Research in Infectious diseases

Instituto de Salud Carlos III- Spanish Network for Research in Infectious Diseases

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01970-21

Reference27 articles.

1. KPC-producing Klebsiella pneumoniae enteric colonization acquired during intensive care unit stay: the significance of risk factors for its development and its impact on mortality