The Oxidative Stress-Induced Hypothetical Protein PG_0686 in Porphyromonas gingivalis W83 Is a Novel Diguanylate Cyclase

Author:

Ximinies Alexia D.1,Dou Yuetan1,Mishra Arunima1,Zhang Kangling2,Deivanayagam Champion3ORCID,Wang Charles1,Fletcher Hansel M.1ORCID

Affiliation:

1. Division of Microbiology & Molecular Genetics, School of Medicine, Loma Linda University, Loma Linda, California, USA

2. Department of Pharmacology, University of Texas Medical Branch, Galveston, Texas, USA

3. Department of Biochemistry and Molecular Genetics, University of Alabama, Birmingham, Alabama, USA

Abstract

Porphyromonas gingivalis is an important etiological agent in periodontitis and other systemic diseases. There is still a gap in our understanding of the mechanisms that P. gingivalis uses to survive the inflammatory microenvironment of the periodontal pocket.

Funder

HHS | NIH | National Institute of Dental and Craniofacial Research

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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