Immunoinformatics Approach to Design Novel Subunit Vaccine against the Epstein-Barr Virus-Reference-Cited by-同舟云学术

Immunoinformatics Approach to Design Novel Subunit Vaccine against the Epstein-Barr Virus

Published:2022-10-26 Issue:5 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Moin Abu Tayab¹²^ORCID,Patil Rajesh B.³,Tabassum Tahani⁴,Araf Yusha¹⁵^ORCID,Ullah Md. Asad⁶,Snigdha Hafsa Jarin⁷,Alam Tawfiq⁸,Alvey Safwan Araf⁹,Rudra Bashudev²,Mina Sohana Akter²,Akter Yasmin²,Zhai Jingbo¹⁰¹¹,Zheng Chunfu¹¹²^ORCID

Affiliation:

1. The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, School of Life Sciences, Inner Mongolia University, Hohhot, China

2. Department of Genetic Engineering and Biotechnology, Faculty of Biological Sciences, University of Chittagong, Chattogram, Bangladesh

3. Department of Pharmaceutical Chemistry, Sinhgad Technical Education Society's, Sinhgad College of Pharmacy, Vadgaon (Bk), Maharashtra, India

4. Biotechnology Program, Department of Mathematics and Natural Sciences, School of Data and Sciences, BRAC University, Dhaka, Bangladesh

5. Department of Biotechnology, Bangladesh Agricultural University, Mymensingh, Bangladesh

6. Department of Biotechnology and Genetic Engineering, Faculty of Biological Sciences, Jahangirnagar University, Savar, Dhaka, Bangladesh

7. Department of Microbiology, School of Environmental and Life Sciences, Independent University Bangladesh

8. Department of Genetic Engineering and Biotechnology, School of Life Sciences, Shahjalal University of Science and Technology, Sylhet, Bangladesh

9. Department of Physics, University of Dhaka, Dhaka, Bangladesh

10. Medical College, Inner Mongolia Minzu University, Tongliao, China

11. Key Laboratory of Zoonose Prevention and Control at Universities of Inner Mongolia Autonomous Region, Tongliao, China

12. Department of Microbiology, Immunology and Infectious Diseases, University of Calgary, Calgary, Alberta, Canada

Abstract

Epstein-Barr virus (EBV) vaccines have been developing for over 30 years, but polyphyletic and therapeutic vaccines have failed to get licensed. Our vaccine surpasses the limitations of many such vaccines and remains very promising, which is crucial because the infection rate is higher than most viral infections, affecting a whopping 90% of the adult population.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.01151-22

Reference152 articles.

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3. Epstein-Barr Virus Sequence Variation—Biology and Disease

4. EBV Persistence in Memory B Cells In Vivo

5. Is EBV Persistence In Vivo a Model for B Cell Homeostasis?

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