Antibiotic Conditioning Shapes Pseudosterile Mouse Models by Deleting Colonic Microbes Rather than Small Intestinal Microbes-Reference-Cited by-同舟云学术

Antibiotic Conditioning Shapes Pseudosterile Mouse Models by Deleting Colonic Microbes Rather than Small Intestinal Microbes

Published:2023-06-15 Issue:3 Volume:11 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Chen Qingxue¹²,Ma Xinming¹²,Xing Zhishuang¹²,Zhao Xin³,Zu Hang⁴,Guo Zengwang¹²,Li Bailiang¹²^ORCID

Affiliation:

1. Key Laboratory of Dairy Science, Ministry of Education, Northeast Agricultural University, Harbin, China

2. Food College, Northeast Agricultural University, Harbin, China

3. CABIO Biotech (Wuhan) Co., Ltd., Wuhan, China

4. Heilongjiang Ubayt Dairy Group Co., Ltd., Qiqihaer, China

Abstract

Many studies have applied antibiotics to delete intestinal microbes to shape pseudosterile mouse models and further used for fecal microbial transplantation. However, few studies have explored the spatial location of antibiotic action in the intestine.

Funder

China Postdoctoral Science Foundation

Young Elite Scientists Sponsorship Program by CAST

National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.00814-23

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