N-Linked Glycosylation and Expression of Duck Plague Virus pUL10 Promoted by pUL49.5

Author:

Li Chunmei12,Wang Mingshu1342,Cheng Anchun1342ORCID,Wu Ying1342,Tian Bin1342,Yang Qiao1342,Gao Qun1342,Sun Di1342,Zhang Shaqiu1342,Ou Xumin1342,He Yu1342,Huang Juan1342,Zhao Xinxin1342,Chen Shun1342,Zhu Dekang342ORCID,Liu Mafeng1342ORCID,Jia Renyong1342

Affiliation:

1. Institute of Veterinary Medicine and Immunology, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu City, Sichuan, China

2. Engineering Research Center of Southwest Animal Disease Prevention and Control Technology, Ministry of Education of the People's Republic of China, Chengdu City, Sichuan, China

3. Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, Chengdu City, Sichuan, China

4. Avian Disease Research Center, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu City, Sichuan, China

Abstract

Duck plague is a disease with high morbidity and mortality rates, and it causes great losses for the duck breeding industry. Duck plague virus (DPV) is the causative agent of duck plague, and DPV UL10 protein (pUL10) is a homolog of glycoprotein M (gM), which is conserved in herpesviruses. pUL10 plays complex roles in viral fusion, assembly, cell-to-cell spread, and immune evasion, which are closely related to its protein characteristics and partners.

Funder

MOA | Earmarked Fund for China Agriculture Research System

China's Agricultural Research System | Sichuan Veterinary Medicine and Drug Innovation Group of China Agricultural Research System

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

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