A Multiplex Noninvasive Salivary Antibody Assay for SARS-CoV-2 Infection and Its Application in a Population-Based Survey by Mail-Reference-Cited by-同舟云学术

A Multiplex Noninvasive Salivary Antibody Assay for SARS-CoV-2 Infection and Its Application in a Population-Based Survey by Mail

Published:2021-10-31 Issue:2 Volume:9 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Egorov Andrey I.¹^ORCID,Griffin Shannon M.²,Fuzawa Miyu¹,Kobylanski Jason¹,Grindstaff Rachel³,Padgett William³,Simmons Steven³,Hallinger Daniel R.³,Styles Jennifer N.¹⁴,Wickersham Lindsay³,Sams Elizabeth¹,Hudgens Edward¹,Wade Timothy J.¹

Affiliation:

1. U.S. Environmental Protection Agency, Chapel Hill, North Carolina, USA

2. U.S. Environmental Protection Agency, Cincinnati, Ohio, USA

3. U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, USA

4. University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

Abstract

Given the enormous impacts of the COVID-19 pandemic, developing tools for population surveillance of infection is of paramount importance. This article describes the development of a multiplex immunoassay on a Luminex platform to measure salivary immunoglobulin G responses to the spike protein, its two subunits and receptor binding domain, and the nucleocapsid protein of SARS-CoV-2.

Funder

Environmental Protection Agency

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/Spectrum.00693-21

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