Failure of Cefepime Therapy in Treatment of Klebsiella pneumoniae Bacteremia-Reference-Cited by-同舟云学术

Failure of Cefepime Therapy in Treatment of Klebsiella pneumoniae Bacteremia

Published:2005-09 Issue:9 Volume:43 Page:4891-4894
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Song Wonkeun¹,Moland Ellen S.¹,Hanson Nancy D.¹,Lewis James S.²,Jorgensen James H.³,Thomson Kenneth S.¹

Affiliation:

1. Center for Research in Antiinfectives and Biotechnology, Department of Medical Microbiology and Immunology, Creighton University School of Medicine, 2500 California Plaza, Omaha, Nebraska 68178

2. Departments of Pharmacology

3. Pathology, The University of Texas Health Science Center, San Antonio, Texas 78229

Abstract

ABSTRACT A case of failure of cefepime treatment of a bloodstream infection with AmpC-producing Klebsiella pneumoniae is reported. The failure was attributed to extended-spectrum β-lactamase (ESBL) acquisition by the isolate, possibly during therapy. Problems encountered with ESBL detection in AmpC-producing isolates are discussed.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.43.9.4891-4894.2005

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