Affiliation:
1. Centre for Microbial Diseases and Immunity Research, Department of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada
Abstract
ABSTRACT
We investigated the transcriptional responses of
Pseudomonas aeruginosa
under phosphate-deficient (0.2 mM) conditions compared to phosphate sufficiency (1 mM). This elicited enormous transcriptional changes in genes related to phosphate acquisition, quorum sensing, chemotaxis, toxin secretion, and regulation. This dysregulation also led to increased virulence-associated phenotypes, including swarming motility and cytotoxicity.
Publisher
American Society for Microbiology
Subject
Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology
Cited by
90 articles.
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