Plaque Assay for Measuring Serum Bactericidal Activity Against Gonococci

Author:

Corbeil Lynete B.1,Wunderlich Annette C.1,Ito James I.1,McCutchan J. Allen1

Affiliation:

1. Department of Medicine, University of California at San Diego, San Diego, California 92103

Abstract

A new semiquantitative plaque assay was developed to measure killing of gonococci by serum. Results compare well with an established quantitative method, but the plaque assay is faster, simpler, and less expensive.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference7 articles.

1. A plaque assay on agar for detection of gram-negative bacilli sensitive to complement;Fierer J.;J. Immunol.,1972

2. Neisseria gonorrhoeae. I. Virulence genetically linked to clonal variation;Kellogg D. S.;J. Bacteriol.,1963

3. Influence of colony type on susceptibility of gonococci to killing by human serum;McCutchan J. A.;J. Immunol.,1976

4. McCutchan J. A. D. Katzenstein D. Norquist G. Chikami A. Wunderlich and A. I. Braude. 1978. Role of blocking antibody in disseminated gonococcal infection p. 181-186. In G. F. Brooks E. C. Gotschlich K. K. Holmes W. D. Sawyer and F. E. Young (ed.) Immunobiology of Neisseria gonorrhoeae. American Society for Microbiology Washington D.C.

5. The bactericidal power of the blood;Miles A. A.;J. Hyg.,1938

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