In Vitro Activities of Clinafloxacin against Contemporary Clinical Bacterial Isolates from 10 North American Centers-Reference-Cited by-同舟云学术

In Vitro Activities of Clinafloxacin against Contemporary Clinical Bacterial Isolates from 10 North American Centers

Published:1998-05 Issue:5 Volume:42 Page:1274-1277
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Fuchs Peter C.¹,Barry Arthur L.¹,Brown Steven D.¹

Affiliation:

1. The Clinical Microbiology Institute, Wilsonville, Oregon 97070

Abstract

ABSTRACT Clinafloxacin was more active than ciprofloxacin against 4,213 aerobic and facultative anaerobic bacterial isolates from 10 medical centers, as tested by broth microdilution and disk diffusion methods. The percentage of 201 anaerobes susceptible to clinafloxacin by broth microdilution was comparable to cefoxitin. Our data support the proposed disk diffusion interpretive criteria for aerobic bacteria with 5-μg clinafloxacin disks.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.42.5.1274

Reference14 articles.

1. The tolerance and pharmacokinetics of clinafloxacin (CI-960) in healthy subjects.;Bron N. J.;J. Antimicrob. Chemother.,1996

2. Activities of three investigational fluoroquinolones (BAY y 3118, DU-6859a, and clinafloxacin) against Neisseria gonorrhoeae isolates with diminished susceptibilities to ciprofloxacin and ofloxacin

3. In vitro and in vivo activities of clinafloxacin, CI-990 (PD 131112), and PD 138312 versus enterococci

4. Multicenter evaluation of the in vitro activities of three new quinolones, sparfloxacin, CI-960, and PD 131,628, compared with the activity of ciprofloxacin against 5,252 clinical bacterial isolates

5. Susceptibility of ciprofloxacin-resistant staphylococci and enterococci to clinafloxacin.;Harrington G. D.;Diagn. Microbiol. Infect. Dis.,1995

Cited by 18 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Bacterial Infections in the Elderly Patient: Focus on Sitafloxacin;Clinical Medicine Insights: Therapeutics;2012-01

2. A Review of New Fluoroquinolones;Treatments in Respiratory Medicine;2006

3. A Critical Review of the Fluoroquinolones;Drugs;2002

4. Drug Interactions with Clinafloxacin;Antimicrobial Agents and Chemotherapy;2001-09

5. Clinafloxacin Pharmacokinetics in Subjects with Various Degrees of Renal Function;Antimicrobial Agents and Chemotherapy;2001-09