Double-Blind Controlled Comparison of Phlebitis Produced by Cephapirin and Cephalothin

Author:

Carrizosa Jaime12,Levison Matthew E.12,Kaye Donald12

Affiliation:

1. Department of Medicine, The Medical College of Pennsylvania, Philadelphia, Pennsylvania 19129

2. Philadelphia Veterans Administration Hospital, Philadelphia, Pennsylvania, 19104

Abstract

In a double-blind study with each patient as his own control cephapirin and cephalothin were administered to 20 patients in opposite arms for a period of 48 hr each. Neither the incidence of phlebitis nor the degree of phlebitis was significantly different with the two drugs, and there was no difference in the time of onset of pain or phlebitis.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference5 articles.

1. Clinical and in vitro evaluation of cephapirin: a new parenteral cephalosporin;Bodner S. J.;Amer. J. Med. Sci.,1972

2. Clinical and in vitro evaluation of cephapirin: a new cephalosporin antibiotic;Bran J. L.;Antimicrob. Ag. Chemother.,1972

3. Laboratory and pharmacologic studies of BL-P-1322 (cephapirin sodium) in children;Gordon R. C.;Curr. Ther. Res.,1971

4. Relative incidence of phlebitis caused by continuous intravenous infusion of cephapirin and cephalothin;Lane A. Z.;Antimicrob. Ag. Chemother.,1972

5. Evaluation of a new cephalosoprin antibiotic, cephapirin;Wiesner P.;Antimicrob. Ag. Chemother.,1972

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