Implications of Bacteriophage- and Bacteriophage Component-Based Therapies for the Clinical Microbiology Laboratory

Author:

Caflisch Katherine M.1,Patel Robin23ORCID

Affiliation:

1. Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA

2. Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA

3. Division of Infectious Diseases, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA

Abstract

Treatment of bacterial infections is increasingly challenged by resistance to currently available antibacterial agents. Not only are such agents less likely to be active today than they were in the past, but their very use has selected for and continues to select for further resistance. Additional strategies for the management of bacterial illnesses must be identified. In this review, bacteriophage-based therapies are presented as one promising approach.

Funder

Antibiotic resistance leadership group

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference68 articles.

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