Genetic Relationships among Reptilian and Mammalian Campylobacter fetus Strains Determined by Multilocus Sequence Typing

Author:

Dingle Kate E.1,Blaser Martin J.2,Tu Zheng-Chao2,Pruckler Janet3,Fitzgerald Collette3,van Bergen Marcel A. P.45,Lawson Andrew J.6,Owen Robert J.6,Wagenaar Jaap A.475

Affiliation:

1. Nuffield Department of Clinical Laboratory Sciences, Oxford University, John Radcliffe Hospital, Oxford OX3 9DU, United Kingdom

2. Department of Medicine, New York University School of Medicine, 550 First Avenue, New York, New York 10016

3. Enteric Diseases Laboratory Branch, CDC, Atlanta, Georgia

4. Central Veterinary Institute of Wageningen UR, P.O. Box 65, 8200 AB Lelystad, Netherlands

5. WHO Collaborating Centre for Campylobacter and OIE-Reference Laboratory for Campylobacteriosis, Lelystad and Utrecht, Netherlands

6. Laboratory of Enteric Pathogens, Centre for Infections, Health Protection Agency, London, United Kingdom

7. Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, Netherlands

Abstract

ABSTRACT Reptile Campylobacter fetus isolates and closely related strains causing human disease were characterized by multilocus sequence typing. They shared ∼90% nucleotide sequence identity with classical mammalian C. fetus , and there was evidence of recombination among members of these two groups. The reptile group represents a possible separate genomospecies capable of infecting humans.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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