Compensation by the E138K Mutation in HIV-1 Reverse Transcriptase for Deficits in Viral Replication Capacity and Enzyme Processivity Associated with the M184I/V Mutations-Reference-Cited by-同舟云学术

Compensation by the E138K Mutation in HIV-1 Reverse Transcriptase for Deficits in Viral Replication Capacity and Enzyme Processivity Associated with the M184I/V Mutations

Published:2011-08-17 Issue:21 Volume:85 Page:11300-11308
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:Journal of Virology

Author:

Xu H.-T.,Asahchop E. L.,Oliveira M.,Quashie P. K.,Quan Y.,Brenner B. G.,Wainberg M. A.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Reference44 articles.

1. The human immunodeficiency virus type 1 nonnucleoside reverse transcriptase inhibitor resistance mutation I132M confers hypersensitivity to nucleoside analogs;Ambrose;J. Virol.,2009

2. Comparison of deoxyoligonucleotide and tRNA(Lys-3) as primers in an endogenous human immunodeficiency virus-1 in vitro reverse transcription/template-switching reaction;Arts;J. Biol. Chem.,1994

3. Characterization of the E138K resistance mutation in HIV-1 reverse transcriptase conferring susceptibility to etravirine in B and non-B HIV-1 subtypes;Asahchop;Antimicrob. Agents Chemother.,2011

4. TMC278, a next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI), active against wild-type and NNRTI-resistant HIV-1;Azijn;Antimicrob. Agents Chemother.,2010

5. Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme;Back;EMBO J.,1996

Cited by 84 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Design and optimization of piperidine-substituted thiophene[3,2-d]pyrimidine-based HIV-1 NNRTIs with improved drug resistance and pharmacokinetic profiles;Acta Pharmaceutica Sinica B;2024-07

2. Structure‐based design of diarylpyrimidines and triarylpyrimidines as potent HIV‐1 NNRTIs with improved metabolic stability and drug resistance profiles;Journal of Medical Virology;2024-03

3. Recent Advances in Pyrimidine-Based Drugs;Pharmaceuticals;2024-01-11

4. 5-Cyano substituted diarylpyridines as potent HIV-1 NNRTIs: Rational design, synthesis, and activity evaluation;European Journal of Medicinal Chemistry;2023-11

5. 1,2,3-triazole derivatives as antiviral agents;Medicinal Chemistry Research;2023-10-09